Comparison of Left Ventricle Deformation Analysis Using Abaqus and CVi42 Software: Insights from Healthy Subjects and patients with Myocardial Infarction

Abstract

Cardiovascular diseases represent a major health problem. The heart is the central organ of this cardiovascular system and can be affected by numerous diseases. For instance, myocardial infarction (MI) is a cardiac condition that occurs when the heart does not receive enough blood and oxygen, this dysfunction typically results in severe myocardial damage. MI alters the mechanical parameters of the heart. Radiologists are unable to detect these mechanical changes. In this context, computational mechanical models of the left ventricle (LV) serve as a useful tool for the diagnosis and treatment of heart failure and other cardiac diseases. The aim of this study is to simulate the Left Ventricle to enhance the identification of cardiac pathologies and improve diagnostic outcomes. An approach based on a computational Finite Element model was developed and evaluated to estimate deformation distribution in healthy subjects and patients with myocardial infarction. The results indicate that deformation measurements can effectively distinguish between healthy and pathological subjects. We measured the range of deformation for a healthy left ventricle (LV) as follows: circumferential deformation at -18.78%, longitudinal deformation at -17.08%, and radial deformation at 33.14%. In patients with myocardial infarction (MI), the average longitudinal deformation was -10.22%, circumferential deformation averaged -11.76%, and radial deformation averaged 17.40%. It is understood that the current research provides important information to clinicians to facilitate diagnosis and treatment of individual patients.