article · RSC Medicinal Chemistry

Combating oxi-inflamm-aging: Passerini adducts tethered with 1,2,3-triazoles for enhanced antioxidant defense and 5-LOX inhibition

20251 citationOpen accessPharos University in Alexandria

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Abstract

ADMET profiling confirmed favorable drug-like properties for these hits, suggesting their potential as probable candidates for combating oxi-inflamm-aging.

Research topics

Bioactive Compounds and Antitumor Agents
Synthesis and biological activity
Computational Drug Discovery Methods

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DOI: 10.1039/d4md00981a

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