article · BMC Microbiology

Coexistence of plasmid-mediated quinolone resistance (PMQR) and extended-spectrum beta-lactamase (ESBL) genes among clinical Pseudomonas aeruginosa isolates in Egypt

202413 citationsOpen accessMinia University

Abstract

A high prevalence of PMQR genes among the phenotypic fluoroquinolone-resistant P. aeruginosa isolates was detected, with the co-carriage of different PMQR genes. The most frequent PMQR was the acc(6')-Ib-cr gene. Co-existence between PMQR and ESBL genes was found, with 75% of PMQR-positive isolates carrying at least one ESBL gene. A high and significant correlation between the ESBL and PMQR genes was detected.

Research topics

Antibiotic Resistance in Bacteria
Antibiotic Use and Resistance
Pharmaceutical and Antibiotic Environmental Impacts

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DOI: 10.1186/s12866-024-03319-z

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