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article · Eurosurveillance

Co-circulation of monkeypox virus subclades Ia and Ib in Kinshasa Province, Democratic Republic of the Congo, July to August 2024

202439 citationsOpen accessUniversité de Kinshasa (UNIKIN)

In plain language

Between January and August 2024, mpox cases were reported across nearly all provinces in the Democratic Republic of the Congo. Researchers obtained monkeypox virus genome sequences from 11 patient samples collected in Kinshasa during July and August 2024. Analysis of these sequences revealed that subclades Ia and Ib of the monkeypox virus were co-circulating within the Limete health zone. Further phylogenetic studies suggested that these two subclades had been introduced into Kinshasa multiple times. This finding underscores the increasing complexity of Clade I mpox outbreaks observed in the DRC.

Key takeaways

  • Mpox cases were widespread across the Democratic Republic of the Congo between January and August 2024.
  • Monkeypox virus genome sequences were analysed from 11 cases in Kinshasa during July-August 2024.
  • Subclades Ia and Ib of the monkeypox virus were found to be co-circulating in Kinshasa's Limete health zone.
  • Phylogenetic analysis indicated multiple introductions of these subclades into Kinshasa.
  • These findings highlight the growing complexity of Clade I mpox outbreaks in the DRC.

Why it matters

Understanding the specific types of monkeypox virus circulating and how they spread is crucial for public health. This research helps track the evolution and movement of the virus, informing strategies to control outbreaks and protect communities from infection.

Commercialisation angle

The abstract focuses on epidemiological findings regarding virus circulation and does not indicate an application pathway for commercialisation.

AI-generated from the published abstract. Always read the original work before citing.

Abstract

Between January and August 2024, mpox cases have been reported in nearly all provinces of the Democratic Republic of the Congo (DRC). Monkeypox virus genome sequences were obtained from 11 mpox cases' samples, collected in July-August 2024 in several health zones of Kinshasa. Characterisation of the sequences showed subclades Ia and Ib co-circulating in the Limete health zone, while phylogenetic analyses suggested multiple introductions of the two subclades in Kinshasa. This illustrates the growing complexity of Clade I mpox outbreaks in DRC.

Research topics

  • Poxvirus research and outbreaks
  • Bacillus and Francisella bacterial research
  • Herpesvirus Infections and Treatments

Read the original research

This page summarises published work. The authoritative version sits with the publisher.

DOI: 10.2807/1560-7917.es.2024.29.38.2400592

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