MARATTO

article · Journal of Social Science and Human Research Studies

Closing the Missing Children Gap: Paediatric Tuberculosis Case-Finding Through School-Based, Child-Led Screening in Kakamega, Kenya

In plain language

This retrospective study evaluated a school-based, child-led tuberculosis screening model implemented in Kakamega, Kenya, between July 2021 and June 2024. Screening reached 266,943 children and diagnosed 214 cases, with all diagnosed individuals successfully linked to treatment. Paediatric cases made up 23.2% of all tuberculosis diagnoses under the programme, surpassing the national benchmark of 10% to 15%. Furthermore, bacteriological confirmation reached 54.7%, exceeding typical global rates of 20% to 30%, although 1,247 children needed to be screened per case found. Crucially, the care cascade showed no significant disparities between girls and boys. The evidence indicates that school-based, child-led screening effectively finds missing paediatric cases without gender bias, justifying the expansion of the approach beyond a pilot phase.

Key takeaways

  • School-based, child-led screening identified 214 paediatric tuberculosis cases among 266,943 children, achieving a 100% treatment linkage rate.
  • Paediatric cases accounted for 23.2% of all detected tuberculosis cases, exceeding the national target range of 10% to 15%.
  • Bacteriological confirmation reached 54.7%, markedly higher than typical international figures of 20% to 30%.
  • No statistically significant sex-based inequities were observed at any stage of the care cascade.
  • The number of children needed to screen to detect one case was 1,247, higher than the pooled global benchmark for school settings.

Why it matters

Paediatric tuberculosis remains chronically underdiagnosed globally, preventing health systems from reaching critical case-finding targets. This research confirms that child-led screening within schools can bridge the missing cases gap effectively. The approach demonstrates that high diagnostic confirmation and complete treatment linkage can be achieved without introducing gender-based inequities, providing health authorities with an actionable strategy to improve child health outcomes.

Commercialisation angle

This work represents an applied and tested public health delivery model ready for wider adoption rather than an unproven pilot. The primary users are national tuberculosis control programmes, health ministries, and non-governmental implementing partners. It provides a validated operational framework for deploying community-level screening in schools to improve case detection and treatment adherence within public health systems.

AI-generated from the published abstract. Always read the original work before citing.

Abstract

Kenya's NTLD-P targets children as 10–15% of all notified tuberculosis (TB) cases, a target the country has struggled to meet. This study examines the paediatric TB care cascade generated by the Kenya Innovation Challenge Tuberculosis (KIC-TB) project's school-based, child-led screening model in Kakamega, asking whether it displays the sex-based inequity previously documented among adults reached by the same programme, and whether its paediatric contribution meets national case-finding benchmarks. This is a retrospective, descriptive and analytical study of programmatic screening data from the NFM3 funding phase (July 2021–June 2024), the period for which complete, sex-disaggregated paediatric records are available. The care cascade: screened, presumptive, investigated, diagnosed, and linked to treatment was analysed by sex using chi-square and Fisher's exact tests, with odds ratios and 95% confidence intervals, and benchmarked against national and global literature. Of 266,943 children screened, 214 were diagnosed with TB (117 bacteriologically confirmed) and all were linked to treatment (100%). No significant sex difference was found at any cascade stage (all p > 0.17). Children accounted for 23.2% of all TB cases diagnosed, exceeding national targets, with bacteriological confirmation (54.7%) above typical global figures (20–30%), though the number needed to screen (1,247) exceeded the pooled global school-setting estimate (464). School-based, child-led screening can close a meaningful share of Kenya's paediatric case-finding gap without introducing sex-based inequity, and current evidence supports expanding this channel rather than treating it as an unproven pilot.

Research topics

  • Tuberculosis Research and Epidemiology
  • Global Maternal and Child Health
  • Malaria Research and Control

Read the original research

This page summarises published work. The authoritative version sits with the publisher.

DOI: 10.65150/ep-jsshrs/v2e8/2026-27

Is something wrong with this record? Report it or request removal.

Discussion

Discuss this research

Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.

No discussion yet. Open the first thread.