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article · International Journal of Medical Science and Dental Health

Chronic Irritation to Malignancy: A Case of Squamous Cell Carcinoma of The Suprapubic Catheter Tract Extending into Bladder in A 46-Year-Old Man.

In plain language

Long-term suprapubic catheterisation can occasionally lead to squamous cell carcinoma along the catheter tract due to persistent irritation, recurrent infections, and tissue changes. A 46-year-old man with a history of traumatic urethral stricture and extended catheter use developed a non-healing ulcer accompanied by bleeding and foul-smelling discharge at his catheter site. Clinical assessments identified an ulcerated mass with local invasion and left-sided hydronephrosis, though no distant spread was detected. Histopathological examination confirmed well-differentiated squamous cell carcinoma. The patient received primary radiotherapy, receiving 65 Gy across 35 fractions, which resulted in near-complete tumor clearance. Persistent ulcers in individuals with long-term catheters require careful monitoring, and primary radiotherapy serves as a possible therapeutic intervention alongside rigorous follow-up.

Key takeaways

  • Squamous cell carcinoma can develop at the suprapubic catheter site as a consequence of chronic irritation and repeated infections.
  • A 46-year-old patient presented with a persistent ulcer, foul-smelling discharge, and hematuria at the catheter insertion tract.
  • Diagnostic imaging and histopathology confirmed a locally invasive, well-differentiated squamous cell carcinoma without distant metastasis.
  • Primary radiotherapy delivering 65 Gy in 35 fractions achieved near-complete resolution of the tumor.

Why it matters

Patients relying on long-term suprapubic catheters face rare risks of malignant transformations driven by chronic inflammation. Documenting such occurrences helps clinicians recognise atypical symptoms early, such as non-healing ulcers and unusual discharge. This awareness supports timely intervention and highlights radiotherapy as an effective management strategy for localized disease.

Commercialisation angle

The abstract does not indicate an application pathway, as it reports a single clinical case study rather than a commercial product, device, or scalable medical technology.

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Abstract

Background: Squamous cell carcinoma (SCC) of the suprapubic cystostomy (SPC) tract is a rare but serious complication of long-term catheterization. Chronic irritation, recurrent infections, and metaplastic changes contribute to its pathogenesis. While SCC of the bladder is well-documented, neoplastic transformation at the SPC site remains uncommon, with limited cases reported in the literature. Case Presentation: A 46-year-old man with a history of traumatic urethral stricture and long-term suprapubic catheterization presented with a non-healing ulcer, hematuria, and foul-smelling discharge at the catheter site. Examination revealed an ulcerated mass, and imaging confirmed local tumor invasion with left-sided hydronephrosis but no distant metastasis. Histopathology confirmed well-differentiated SCC. The patient underwent primary radiotherapy (65 Gy in 35 fractions), leading to near-complete tumor resolution. Conclusion: This case highlights the need for vigilance in patients with chronic SPC use who present with persistent ulcerative lesions. Primary radiotherapy may be a viable treatment option. Close surveillance remains crucial to monitor for recurrence.

Research topics

  • Palliative Care and End-of-Life Issues

Read the original research

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DOI: 10.55640/ijmsdh-11-06-05

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