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article · Biological Psychiatry

Childhood Maltreatment and Deviations from Normative Brain Structure: A Mega-Analysis of 3,711 Individuals from the ENIGMA MDD and ENIGMA PTSD Working Groups

Abstract

Our findings of age- and sex-specific instantiations of CM on brain morphometry highlight the importance of developmental context in understanding how adverse experiences shape neurobiological vulnerability to MDD and PTSD.

Research topics

  • Child Abuse and Trauma
  • Posttraumatic Stress Disorder Research
  • Child Abuse and Related Trauma

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DOI: 10.1016/j.biopsych.2026.02.016

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