article · Reports of Biochemistry and Molecular Biology

Celastrol Mitigates Acetaminophen-Induced Nephrotoxicity in Rats via Targeting Renal Oxidative Stress, Inflammation, Apoptosis with Enhancement in Aquaporin 1 Level

Mohie Mahmoud Ibrahim
Mohammad El-Kattan
Azza I. Helal
Iman Ibrahim
Alaa M. Badawy
Sara Abubakr
Amira Osman
Ahmed Abdel-monem Elmetwally
Ahmed Mohsen Faheem
Emadeldeen Hussin

20243 citationsOpen accessKafr el-Sheikh University

In plain language

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Abstract

We provided a novel treatment against acetaminophen induced-nephrotoxicity with targeting renal oxidative stress, inflammation, apoptosis with elevation of Aquaporin 1 (AQP1) level.

Research topics

Natural Compounds in Disease Treatment
Pharmacological Effects and Toxicity Studies
Drug-Induced Hepatotoxicity and Protection

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DOI: 10.61186/rbmb.13.2.204

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