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article · The Pediatric Infectious Disease Journal

Body Composition Changes in Children Living With HIV Initiated on Dolutegravir or Protease Inhibitors in the CHAPAS-4 Trial

Abstract

DTG and ATV/r were associated with greater gains in fat-free mass and muscle mass than LPV/r, while DRV/r, TAF and prior nevirapine exposure were associated with fat mass accrual. Fat gain may initially reflect return to health but sustained increases may have metabolic implications. These findings suggest the need to monitor fat compartments with long-term exposure.

Research topics

  • HIV-related health complications and treatments
  • Nutrition and Health in Aging
  • HIV/AIDS drug development and treatment

Sustainable Development Goals

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DOI: 10.1097/inf.0000000000005195

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