ASSOCIATION OF INTESTINAL PARASITES WITH HELICOBACTER PYLORI INFECTION IN PATIENT ATTENDING BENHA UNIVERSITY HOSPITAL

Abstract

This cross sectional study was conducted from October 2023 to March 2024, on 170 patientsattending Gastroenterology outpatient clinic in Benha University hospital and aimed to investigatethe association of intestinal parasites with H. pylori infection and the associated symptoms.Stool samples were collected and examined within an hour by: direct wet smear technique,concentration method and Modified Ziehl-Neelsen stain. A rapid chromatographic immuno- assaywas used for the qualitative detection of H. pylori copro-antigens in stool. All patients withaged ranged from 20 to 60 years old, were 73 males (42.94%) and 97 females (57.06%) presentingwith gastrointestinal manifestations.The results showed that 103 (60.59%) patients were positive H. pylori copro-antigen in stooland 24 (14.12%) had different intestinal parasites. There was a significant association betweenintestinal parasites and H. pylori infection (P= 0.0001). Besides, intestinal parasites were associatedwith H. pylori were in (18.45%) of positive patients, and in (7.46%) of H. pylori negativepatients.There was significant difference for different types of intestinal parasites as regarding H. pyloriinfection (P=0.007). Entamoeba histolytica 11 (10.68%) were the most frequently detected parasitein association with H. pylori, followed by Giardia lamblia 5 (4.85%) and Enterobius vermicularis2 (1.9%).