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review · Expert Opinion on Drug Metabolism & Toxicology

Association of GST polymorphism with adverse drug reactions: an analysis across multiple drug categories

20244 citationsMohammed V University

Abstract

According to the existing literature, the association between genetic polymorphisms in GST theta (GSTT1), GST mu (GSTM1), and GST pi (GSTP1) and adverse drug reaction occurrence has been frequently reported. However, the strength of these associations varies considerably among studies, with some showing inconsistent or contradictory results, underscoring the need for further investigations.

Research topics

  • Glutathione Transferases and Polymorphisms
  • Pharmacogenetics and Drug Metabolism
  • Folate and B Vitamins Research

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DOI: 10.1080/17425255.2024.2426616

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