article · Malaria Journal

Assessment of Plasmodium falciparum anti-malarial drug resistance markers in pfk13-propeller, pfcrt and pfmdr1 genes in isolates from treatment failure patients in Democratic Republic of Congo, 2018–2019

Doudou Malekita Yobi
Hippolyte Situakibanza
Dieudonné Makaba Mvumbi
Georges Lelo Mvumbi
Niko Speybroeck
Pius Zakayi Kabututu
Patrick De Mol
Solange E. Umesumbu
Raphaël Boreux
Nadine Kalenda Kayiba
Marie‐Pierre Hayette

202120 citationsOpen accessUniversité de Kinshasa (UNIKIN)

Abstract

No molecular markers currently known to be associated with resistance to the first-line ACT in use were detected in isolates of P. falciparum from treatment failure patients. Regular monitoring through in vivo drug efficacy and molecular studies must continue to ensure the effectiveness of malaria treatment in Democratic Republic of Congo.

Research topics

Malaria Research and Control
Computational Drug Discovery Methods
Drug-Induced Hepatotoxicity and Protection

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1186/s12936-021-03636-y

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