review · Journal of Functional Biomaterials
Strontium is a divalent metallic element with properties comparable to trace elements naturally present in human bone. Because its atomic radius resembles that of calcium, it can readily substitute for calcium in diverse calcium-containing biomaterials. It supports bone maintenance by suppressing bone resorption while simultaneously stimulating bone deposition, characteristics that have established its value in osteoporosis treatments. Within dental science, strontium serves multiple practical roles. It acts as an effective radiopacifier, incorporated into clinical materials to enhance their visibility under diagnostic imaging. In addition, strontium additions enhance the mechanical strength and antimicrobial capabilities of dental formulations. The element also assists in oral tissue repair by promoting enamel remineralisation, alleviating dentin hypersensitivity, and supporting the active regeneration of dentin.
Dental materials require durability, clear visibility on clinical scans, and compatibility with natural tooth structures. Strontium provides multiple functional benefits in a single additive by strengthening dental materials, combating bacteria, and enhancing imaging clarity. Furthermore, its capacity to remineralise enamel, reduce tooth sensitivity, and stimulate dentin regeneration supports oral care interventions that actively preserve and rebuild natural dental tissues.
The findings are relevant to manufacturers of dental composites, cements, and oral care products treating sensitivity or enamel decay. Strontium is already incorporated into existing dental materials to improve radiopacity, indicating applied and mature use for imaging. Other uses, such as enhancing dentin regeneration and antimicrobial performance, point to ongoing opportunities for dental device developers, though the review format encompasses varying stages of commercial readiness across these distinct applications.
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Divalent cations have captured the interest of researchers in biomedical and dental fields due to their beneficial effects on bone formation. These metallic elements are similar to trace elements found in human bone. Strontium is a divalent cation commonly found in various biomaterials. Since strontium has a radius similar to calcium, it has been used to replace calcium in many calcium-containing biomaterials. Strontium has the ability to inhibit bone resorption and increase bone deposition, making it useful in the treatment of osteoporosis. Strontium has also been used as a radiopacifier in dentistry and has been incorporated into a variety of dental materials to improve their radiopacity. Furthermore, strontium has been shown to improve the antimicrobial and mechanical properties of dental materials, promote enamel remineralization, alleviate dentin hypersensitivity, and enhance dentin regeneration. The objective of this review is to provide a comprehensive review of the applications of strontium in dentistry.
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DOI: 10.3390/jfb15080216
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