Antibacterial activity of ethanolic extracts of Thymus vulgaris and Cinnamomum camphora on human pathogenic bacteria.

Abstract

Medicinal Various chemical compounds produced by herbs have primary medicinal uses, particularly in treating bacterial diseases, such as nosocomial infections. Thymus Vulgaris Cinnamomum camphora ethanolic extracts were investigated for their antibacterial activity against three hazardous bacteria: Staphylococcus aureus, Acinetobacter baumannii complex, and Klebsiella pneumoniae. The three dangerous bacteria—Staphylococcus aureus, Acinetobacter baumannii complex, and Klebsiella pneumoniae—were detected utilizing the 16rRNA gene extracted from clinical specimens (pneumonia, sputum, urine). Two Egyptian plant extracts, ethanolic (Thymus vulgaris) and the other Cinnamomum camphora, were tested in vitro for antibacterial activity. The Thymus Vulgaris extract showed main inhibition diameters of 27, 30.3, and 20.6 mm against three human pathogenic bacteria, while the Cinnamomum camphora extract showed main inhibition diameters of 25, 27.6, and 18.3 mm. The gas chromatography-mass spectrometry (GC-MS) examination of the Thymus Vulgaris Cinnamomum camphora extracts indicated the presence of several terpene compounds. The main ingredient (in this order: cis-vaccenic acid, otadecanoic acid, cis-13-eicosenoic acid, erucic acid, oleic acid, 13-docosenoic acid, isochlapin B, thymol, epiplobol).