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article · Antibodies

An Improved Theileria parva Sporozoite Seroneutralization Assay for the Identification of East Coast Fever Immune Correlates

20242 citationsOpen accessUniversity of Nairobi

Abstract

This effect is described for the first time in <i>Theileria parva</i> and is of great interest for new antigen discovery and/or the epitope discovery of already known antigens like p67, opening a new avenue for the identification of ECF immune correlates of protection and the in vitro down-selection of new <i>Theileria parva</i> vaccine candidates, thereby contributing to reducing the use of animals in challenge experiments.

Research topics

  • Vector-borne infectious diseases
  • Vector-Borne Animal Diseases
  • Mosquito-borne diseases and control

Sustainable Development Goals

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DOI: 10.3390/antib13040100

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