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Abstract Brain tumors are one of the most life-threatening diseases, requiring precise and timely detection for effective treatment. Traditional methods for brain tumor detection rely heavily on manual analysis of MRI scans, which is time-consuming, subjective, and prone to human error. With advancements in deep learning, Convolutional Neural Networks (CNNs) have become popular for medical image analysis. However, CNNs are limited in their ability to capture spatial hierarchies and pose variations, which reduces their accuracy, particularly for tasks like brain tumor segmentation where precise spatial relationships are crucial. This research introduces a hybrid Capsule Neural Network (CapsNet) and ResNet50 model designed to overcome the limitations of traditional CNNs by capturing both spatial and pose information in MRI scans. The proposed model leverages ResNet50 for feature extraction and CapsNet for handling spatial relationships, leading to more accurate segmentation. The study evaluates the model on the BraTS2020 dataset and compares its performance to state-of-the-art CNN architectures, including U-Net and pure CNN models. The hybrid model, featuring a custom 5-cycle dynamic routing algorithm to enhance capsule agreement for tumor boundaries, achieved 98% accuracy and an F1-score of 0.87, demonstrating superior performance in detecting and segmenting brain tumors. This study pioneers the systematic evaluation of the ResNet50 + CapsNet hybrid on the BraTS2020 dataset, with a tailored class weighting scheme addressing class imbalance, improving effectiveness in identifying irregularly shaped tumors and smaller regions in identifying irregularly shaped tumors and smaller tumor regions. The study offers a robust solution for automating brain tumor detection. Future work will explore the use of Capsule Networks alone for brain tumor detection in MRI data and investigate alternative Capsule Network architectures, as well as their integration into clinical decision support systems.
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DOI: 10.64898/2026.02.05.26345460
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