A Systematic Review for Difference between Free and Pedicle Recycling Bone Autograft in Limb Reconstruction in Bone Tumors

Abstract

Abstract Background The use of liquid nitrogen for management of the primary lesion in osteosarcoma, was first described in 1984. Surgical use of liquid nitrogen was first reported by Cooper 91 in 1962. Since then, many tumors have been treated locally with liquid nitrogen. Aim of the Work The aim of this study is to review systematically studies to show if there is a difference between pedicle and free freezing in liquid nitrogen in reconstruction after long bone tumors in union and complication. Patients and Methods Between 1999 and 2020 about 235 patient had limb salvage procedure by recycling of bone bearing tumor in liquid nitrogen out of them 205 patient included in this study were inclusion criteria are: Humans: male and female, age from 4 to 80 years, patients with malignant bone tumors either primary or secondary, different methods of fixation are included and minimal follow up of 12 months. Results There are two techniques to recycle bone bearing tumor in liquid nitrogen ether FFP through en block resection of bone bearing tumor and to be recycled separately in liquid nitrogen then fixed in proximal and distal endes OR PFP through performing one side osteotomy maintaining the continuity of the bone with the body and emerge the bone bearing segment in liquid nitrogen and then fix the segment in it’s posttion after completing the recycling. Conclusion We searched to clarify differences between these two methods systematically regarding union time, functional scores, outcoms and complications as infection, graft failure, recurrence & skin necrosis.