A COMPARATIVE STUDY OF CHANGES IN IMMUNOGLOBULINS LEVELS IN PATIENTS WTH IDDM 1 AND NIDDM 2 TYPES OF DIABETES

Abstract

Diabetes mellitus (DM) is defined as a disease that results from an increase in the levelof glucose in the blood (Hyperglycemia) over the normal level as a result of lack orreduction of insulin hormone secretion (from the beta cells of islets of Langerhanslocated within the pancreas) of most vertebrates. Also, it occurs if there is a weaknessin the insulin mechanism of action, or both together. In addition, the defect in theInsulin receptors as a result of epidemiological genetic disorders. Diabetes mellitus iscaused as a result of the deficiency of β cells in the pancreas, so the production ofinsulin by these cells is either little or no, and this is known as Type 1 diabetes mellitusinsulin-dependent diabetes mellitus (IDDM 1). The body's use of insulin correctly(insulin resistance) is known as type 2 diabetes mellitus noninsulin-dependent diabetesmellitus (NIDDM 2). The work aims to Evaluate some immunological indicators andknowledge of the immunological effects of type 1 diabetics and knowledge of therelationship of age, sex, and duration of disease for patients.